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Research activity

Determination of basic thermodynamic and transport properties of the system, which are required for process design including experimental determination of phase equilibria, mass transfer study and modelling by the use of thermodynamic and empirical models.

Design and optimization of conventional and high pressure processes such as:

  • Extraction and adsorption processes for isolation and concentration of active ingredients from natural materials; in vitro testings of antimicrobial and antioxidative activities of extracts from natural materials.
  • E nzyme catalyzed reactions for development of new synthesis paths by the use of high pressure reactors.
  • Development of new processes and nanostructured materials for immobilization of biological compounds.
  • Materials processing, production of micro and nanostructured materials by PGSSTM process, and aerogels for development of new hightech products.
  • Analytical and preparative chromatography with supercritical fluids.

Transfer of processes into industrial scale



  • High pressure extraction plants in laboratory and pilot scale
  • High pressure vessels and view cells for determination of phase equilibria in systems solid-liquid and liquid-liquid
  • High pressure magnetic balance
  • High pressure batch reactors
  • High pressure enzyme reactors: stirred batch reactor, continious flat shape and tubular membrane reactor
  • High pressure pumps
  • Analytical and preparative supercritical chromatograph with UV-VIS detector
  • Equipment for high pressure micronization processes in laboratory and pilot scale (PGSSTM plant)
  • Rectification column
  • Instruments for high performance liquid chromatography (HPLC)
  • UV-VIS spectrophotometer
  • Instrument for measurements of optical density, fluorescence and luminescence
  • Laser granulometer
  • Climatic test cabinets
  • Freeze-dryer
  • Laminar cabinet
  • Incubators
  • Avtoclave for sterilization
  • Porosymeter (N2 adsorption/desorption measurements
  • Dinamic scanning calorimetry (DSC)



Research Programme Group

  • P2 – 0046: Separation processes and production design (Pricipal researcher: Prof. Dr. Željko Knez)

ARRS projects

  • Magnetic nanoparticles as potential carriers of biologically active substances (Pricipal researcher: Prof. Dr. Maja Leitgeb)
  • Processing of polymers using sustainable technology (Pricipal researcher: Prof. Dr. Željko Knez)

7th EU Framework programmes

  • Eurostar Eureka project MOSS - Supercritical Aqueous Reforming of Moist Sewage Sludge a Sustainable Energy Concept for Sewage Treatment Plants (STPs) (Pricipal researcher: Prof. Dr. Željko Knez)
  • Marie Curie Networks for Initial Training (ITN) - Training Program for the Design of Resource and Energy Efficient Products by High Pressure Processes (DoHip) (Pricipal researcher: Prof. Dr. Željko Knez)

Bilateral cooperations

  • Turkey - Slovenia - Flavour of Boz Type Pistachio Nuts: Application of new versatile technologies for isolation and concetration of volatiles and for sensory descriptive analyses (Pricipal researcher: Prof. Dr. Željko Knez)
  • China - Slovenia - Extraction of bioactive compounds from marigold and red peppers with supercritical fluids (Pricipal researcher: Prof. Dr. Željko Knez)